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Stem Cells, Vol 13, 393-403, Copyright © 1995 by AlphaMed Press

REVIEWS

Antigens recognized on human tumors by cytolytic T lymphocytes: towards vaccination?

PG Coulie
Ludwig Institute for Cancer Research, Brussels Branch, Belgium.

It has been known for many years that cytolytic T lymphocytes that specifically recognize the tumor cells of the same patient can be derived from the blood of melanoma patients. Several of the antigens recognized by these antitumor T lymphocytes have now been completely identified. Some of them are sufficiently tumor-specific to envision their use as antitumor vaccines in selected cancer patients.




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Copyright © 1995 by AlphaMed Press.