Files in this Data Supplement:

• Supplemental Figure F
• Supplemental Figure S
• Supplemental Figure A
• Supplemental Figure B
• Supplemental Figure C
• Supplemental Figure D
• Supplemental Figure E
• Supplemental Figure G
• Supplemental Figure H
• Supplemental Figures F-N
• Supplemental Figures O-S
• Supplemental Figure I
• Supplemental Figure M
• Supplemental Figure N
• Supplemental Table A
• Supplemental Figure J
• Supplemental Figure K
• Supplemental Figure L
• Supplemental Figure O
• Supplemental Figure P
• Supplemental Figure Q
• Supplemental Figure R