Submitted on June 28, 2006
Accepted on January 5, 2007
A Meeting Report: "New Technologies in Stem Cell Research"
Jerry C. Cheng 1,
Kathleen M. Sakamoto 2*,
Edwin M. Horwitz 3,
Stanislav L. Karsten 4,
Lorelei Shoemaker 5,
Harley I. Kornblum 6,
Punam Malik 7
1 Division of Hematology/Oncology, Department of Pediatrics, Gwynne Hazen Cherry Memorial Laboratories, and Mattel Children's Hospital, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, California
2 Division of Hematology/Oncology, Department of Pediatrics, Gwynne Hazen Cherry Memorial Laboratories, and Mattel Children's Hospital, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, California; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California; Division of Biology, California Institute of Technology, Pasadena, California
3 St. Jude Children's Research Hospital, Memphis, Tennessee
4 Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, California
5 The Interdepartmental Program in the Neurosciences, David Geffen School of Medicine at UCLA, Los Angeles, California
6 Psychiatry, Pharmacology and Pediatrics, and The Semel Institute for Neuroscience, David Geffen School of Medicine at UCLA, Los Angeles, California
7 Saban Research Institute, Division of Hematology-Oncology, Children's Hospital Los Angeles, Department of Pediatrics and Pathology, University of Southern California Keck School of Medicine, Los Angeles, California
* To whom correspondence should be addressed. E-mail: kms{at}ucla.edu.
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Abstract |
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This is a meeting report on the workshop "New Technologies in Stem Cell Research," which was presented to pediatric residents, fellows, and faculty at the Society for Pediatric Research meeting in San Francisco, California, on April 29, 2006. Four speakers presented an overview of selected topics related to the current status of methods used to study stem cells. The topics presented at the workshop focused on RNA interference, mesenchymal stem cells, expression analysis, and gene therapy.
In the first report, Drs. Jerry Cheng and Kathleen Sakamoto summarize the application of RNA interference in stem cells. Second, Dr. Edwin Horwitz describes basic approaches to the isolation and purification of mesenchymal stem cells. Third, Drs. Stanislav Karsten, Lorelei Shoemaker, and Harley I. Kornblum discuss methods in expression analysis of stem cells. Fourth, Dr. Punam Malik reports on the use of gene therapy for hemoglobinopathies using autologous stem cells.
