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Contents: Volume 26, Number 7



Tissue-Specific Stem Cells

Concise Review: Pax6 Transcription Factor Contributes to both Embryonic and Adult Neurogenesis as a Multifunctional Regulator
Noriko Osumi, Hiroshi Shinohara, Keiko Numayama-Tsuruta, Motoko Maekawa

Molecular Mechanism of Systemic Delivery of Neural Precursor Cells to the Brain: Assembly of Brain Endothelial Apical Cups and Control of Transmigration by CD44
Christine Rampon, Nicolas Weiss, Cyrille Deboux, Nathalie Chaverot, Florence Miller, Delphine Buchet, Helene Tricoire-Leignel, Sylvie Cazaubon, Anne Baron-Van Evercooren, Pierre-Olivier Couraud

Transforming Growth Factor beta Cooperates with Persephin for Dopaminergic Phenotype Induction
Eleni Roussa, Oliver Oehlke, Belal Rahhal, Stephan Heermann, Stefanie Heidrich, Michael Wiehle, Kerstin Krieglstein

Novel Cardiac Precursor-Like Cells from Human Menstrual Blood-Derived Mesenchymal Cells
Naoko Hida, Nobuhiro Nishiyama, Shunichiro Miyoshi, Shinichiro Kira, Kaoru Segawa, Taro Uyama, Taisuke Mori, Kenji Miyado, Yukinori Ikegami, ChangHao Cui, Tohru Kiyono, Satoru Kyo, Tatsuya Shimizu, Teruo Okano, Michiie Sakamoto, Satoshi Ogawa, Akihiro Umezawa

Lineage Selection of Functional and Cryopreservable Human Embryonic Stem Cell-Derived Neurons
Julia Ladewig, Philipp Koch, Elmar Endl, Banu Meiners, Thoralf Opitz, Sebastien Couillard-Despres, Ludwig Aigner, Oliver Brustle

Lentiviral-Transduced Human Mesenchymal Stem Cells Persistently Express Therapeutic Levels of Enzyme in a Xenotransplantation Model of Human Disease
Todd E. Meyerrose, Marie Roberts, Kevin K. Ohlemiller, Carole A. Vogler, Louisa Wirthlin, Jan A. Nolta, Mark S. Sands

CD117-Positive Cells in Adult Human Heart Are Localized in the Subepicardium, and Their Activation Is Associated with Laminin-1 and alpha 6 Integrin Expression
Clotilde Castaldo, Franca Di Meglio, Daria Nurzynska, Gianpaolo Romano, Ciro Maiello, Ciro Bancone, Patrick Muller, Michael Bohm, Maurizio Cotrufo, Stefania Montagnani

Downregulation of Signal Transducer and Activator of Transcription 5 (STAT5) in CD34+ Cells Promotes Megakaryocytic Development, Whereas Activation of STAT5 Drives Erythropoiesis
Sandra G. Olthof, Szabolcs Fatrai, A. Lyndsay Drayer, Monika R. Tyl, Edo Vellenga, Jan Jacob Schuringa

A Novel Isolation Technique of Progenitor Cells in Human Corneal Epithelium Using Non-Tissue Culture Dishes
Seiichi Yokoo, Satoru Yamagami, Takashi Shimada, Tomohiko Usui, Taka-aki Sato, Shiro Amano, Makoto Araie, Junji Hamuro

Ex Vivo Pretreatment with Melatonin Improves Survival, Proangiogenic/Mitogenic Activity, and Efficiency of Mesenchymal Stem Cells Injected into Ischemic Kidney
Celine Mias, Elodie Trouche, Marie-Helene Seguelas, Fabien Calcagno, Francoise Dignat-George, Florence Sabatier, Marie-Dominique Piercecchi-Marti, Laurent Daniel, Pascale Bianchi, Denis Calise, Philippe Bourin, Angelo Parini, Daniel Cussac

Mood Stabilizing Drugs Expand the Neural Stem Cell Pool in the Adult Brain Through Activation of Notch Signaling
Mikito Higashi, Noriko Maruta, Alan Bernstein, Kazuhiro Ikenaka, Seiji Hitoshi

Hepatocyte Nuclear Factor-1 as Marker of Epithelial Phenotype Reveals Marrow-Derived Hepatocytes, but Not Duct Cells, After Liver Injury in Mice
E. Scott Swenson, Ian Guest, Zoran Ilic, Maria Mazzeo-Helgevold, Pablo Lizardi, Camille Hardiman, Stewart Sell, Diane S. Krause

The Lineage--c-Kit+Sca-1+ Cell Response to Escherichia coli Bacteremia in Balb/c Mice
Ping Zhang, Steve Nelson, Gregory J. Bagby, Robert Siggins II, Judd E. Shellito, David A. Welsh

Adult Human Dental Pulp Stem Cells Differentiate Toward Functionally Active Neurons Under Appropriate Environmental Cues
Agnes Arthur, Grigori Rychkov, Songtao Shi, Simon Andrea Koblar, Stan Gronthos

BM88/Cend1 Expression Levels Are Critical for Proliferation and Differentiation of Subventricular Zone-Derived Neural Precursor Cells
Lida Katsimpardi, Maria Gaitanou, Cecile E. Malnou, Pierre-Marie Lledo, Pierre Charneau, Rebecca Matsas, Dimitra Thomaidou



Cancer Stem Cells

Accumulation of Malignant Renal Stem Cells Is Associated with Epigenetic Changes in Normal Renal Progenitor Genes
Sally Metsuyanim, Naomi Pode-Shakked, Kai M. Schmidt-Ott, Gilmor Keshet, Gideon Rechavi, Danith Blumental, Benjamin Dekel

Hypoxia Enhances Tumor Stemness by Increasing the Invasive and Tumorigenic Side Population Fraction
Bikul Das, Rika Tsuchida, David Malkin, Gideon Koren, Sylvain Baruchel, Herman Yeger



Embryonic Stem Cells

Molecular Signature of Cardiomyocyte Clusters Derived from Human Embryonic Stem Cells
Jane Synnergren, Karolina Akesson, Kerstin Dahlenborg, Hilmar Vidarsson, Caroline Ameen, Daniella Steel, Anders Lindahl, Bjorn Olsson, Peter Sartipy

Embryonic Stem Cells as a Platform for Analyzing Neural Gene Transcription
Xiaodong Zhang, Scott A. Horrell, Deany Delaney, David I. Gottlieb

Costimulation Blockade Induces Tolerance to HESC Transplanted to the Testis and Induces Regulatory T-Cells to HESC Transplanted into the Heart
Karl-Henrik Grinnemo, Rami Genead, Makiko Kumagai-Braesch, Agneta Andersson, Christian Danielsson, Agneta Mansson-Broberg, Goran Dellgren, Anne-Marie Stromberg, Henrik Ekberg, Outi Hovatta, Christer Sylven, Matthias Corbascio

Promotion of Feeder-Independent Self-Renewal of Embryonic Stem Cells by Retinol (Vitamin A)
Liguo Chen, Jaspal S. Khillan

Paraxial Mesodermal Progenitors Derived from Mouse Embryonic Stem Cells Contribute to Muscle Regeneration via Differentiation into Muscle Satellite Cells
Hidetoshi Sakurai, Yayoi Okawa, Yuta Inami, Naomi Nishio, Ken-ichi Isobe

Derivation of Euploid Human Embryonic Stem Cells from Aneuploid Embryos
Neta Lavon, Kavita Narwani, Tamar Golan-Lev, Nicole Buehler, David Hill, Nissim Benvenisty

Efficient Production of Mice from Embryonic Stem Cells Injected into Four- or Eight-Cell Embryos by Piezo Micromanipulation
Junjiu Huang, Kai Deng, Haojia Wu, Zhong Liu, Zhisheng Chen, Shanbo Cao, Lingjun Zhou, Xiaoying Ye, David L. Keefe, Lin Liu

alpha -Chemokines Regulate Proliferation, Neurogenesis, and Dopaminergic Differentiation of Ventral Midbrain Precursors and Neurospheres
Linda C. Edman, Helena Mira, Alejandro Erices, Seth Malmersjo, Emma Andersson, Per Uhlen, Ernest Arenas



Translational and Clinical Research

Impact of Myocardial Infarct Proteins and Oscillating Pressure on the Differentiation of Mesenchymal Stem Cells: Effect of Acute Myocardial Infarction on Stem Cell Differentiation
Sung-A Chang, Eun Ju Lee, Hyun-Jae Kang, Shu-Ying Zhang, Ji-Hyun Kim, Lian Li, Seock-Won Youn, Choon-Soo Lee, Keum-Hyun Kim, Joo-Yun Won, Jong-Woo Sohn, Kyung-Woo Park, Hyun-Jai Cho, Sung-Eun Yang, Won Il Oh, Yoon Sun Yang, Won-Kyung Ho, Young-Bae Park, Hyo-Soo Kim

Bone Marrow-Derived Mesenchymal Stem Cells Ameliorate Autoimmune Enteropathy Independently of Regulatory T Cells
Biju Parekkadan, Arno W. Tilles, Martin L. Yarmush


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